“We used the edits that we know are safe because they exist in living dogs… to bring back the direwolf light-colored coat.”

Dr. Beth Shapiro · Huberman Lab · Bringing Extinct Species Back to Life | Dr. Beth Shapiro

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What was described

Used safe coat-color edits known from light-colored domestic dogs to give the engineered dire wolf a light coat without causing albinism

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“We have 20 edits that we picked… we engineered those changes into a gray wolf genome to recreate the dire wolf.”
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“We have 20 edits that we picked, and we sequenced genomes from fossil dire wolves… we engineered those changes into a gray wolf genome to recreate the dire wolf”
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