“We start to encounter lots of these motifs... it really helps you evaluate and troubleshoot even your protein production process”

Latent Space: The AI Engineer Podcast · Lab-in-the-Loop at Compute Speed - Ian Quigley, Leash Bio

Play from 17:20
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What was described

screen every chemical library against hundreds of protein targets to characterize library behavior and troubleshoot protein production

Said nearby on the same subject

“For every 100 calories of pure protein... we are only ever able to use 70 calories, 30 calories for every 100 calories of protein we eat is given off as heat.”
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Said on Thriving Minds with Alberto Zandi
Hard number 30% of protein calories Share this moment
“We had this growing collection of activity cliffs and profiles of the same chemical material across large numbers of proteins”
IQ
Ian Quigley Leash Bio
Latent Space: The AI Engineer Podcast ·
Data play Share this moment
“We've gone directly from chemical library hits to good PKPD in a mouse in six months with a very small number of medchem cycles”
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Said on Latent Space: The AI Engineer Podcast
Hard number 6 months, very small number of medchem cycles Share this moment
“‘16 is the percent of protein we probably need… for most of us healthy individuals, 16% of your total energy intake should probably be protein.’”
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Said on Thriving Minds with Alberto Zandi
Why it worked 16% Share this moment

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